ABSTRACT
@#AIM: To study the correlation between type A behavior and dry eye.<p>METHODS: Here we used case-control study,100 dry eye patients and 100 healthy persons all completed the questionnaire of type A behavior and unified questionnaire. The results were analyzed by univariate and multivariate conditional logistic regression analysis. <p>RESULTS: There was significant difference on distribution of behavior pattern between dry eye group and normal group(<i>χ</i>2=6.494,<i>P</i>=0.011). After one factor logistic regression analysis, the risk of dry eye for people with type A behavior was higher(<i>OR</i>=2.296, 95%<i>CI</i>:1.202-4.384, <i>P</i>=0.012); that for people using visual display terminal more than 6h was 2.992(95%<i>CI</i>:1.668-5.369, <i>P</i><0.01); that for people staying in air condition room was 2.631(95%<i>CI</i>: 1.472-4.702, <i>P</i>=0.001). After multivariate conditional logistic regression analysis, compared with type B behavior, type A behavior pattern(<i>OR</i>=2.659,95%<i>CI</i>:1.335-5.295,<i>P</i>=0.005), people using visual display terminal more than 6h(<i>OR</i>=2.264, 95%<i>CI</i>: 1.166-4.396, <i>P</i>=0.016), people staying in air condition room(<i>OR</i>=2.053, 95%<i>CI</i>: 1.048～4.020, <i>P</i>=0.036)were more significantly associated with dry eye. <p>CONCLUSION: Type A behavior pattern, using visual display terminal more than 6h and staying in air condition room may be independent risk factors for dry eye.
ABSTRACT
@#Ciliary neurotrophic factor(CNTF)is one of the most studied neurotrophic factors. Encapsulated cell technology provides a safe and effective route for the clinical application of CNTF. A large body of evidence shows that CNTF has a neuroprotective effect on glaucoma, age-related macular degeneration, optic nerve injury and other eye diseases. This review focuses on the potential clinical application of CNTF in eye diseases.